Printable paper-based diagnostics

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

Abstract

We applied papermaking techniques to modify the structural properties of the cellulose fiber network in an attempt to design inexpensive, easy-to-use and disposable paper-based analytical devices. The ability of the paper to wick liquids by capillary action was exploited in the development of lateral flow test device. The paper grade was evaluated to meet the needs for sustainable flow of liquids, stability in wetting conditions, brightness and homogeneity. Biofunctionalization of the modified paper was achieved through inkjet printing methods. We show that it was possible to control the fluidic properties of paper to support the transport of fluids and detection particles, to immobilize antibodies on paper by simple physical adsorption and to detect the analyte in clinically relevant ranges. This research was conducted towards the development and design of paper-based diagnostics in the fields of health, well-being, veterinary and environmental point-of-care diagnostics, where the main focus is versatility, novel test formats and low-cost mass production.
Original languageEnglish
Title of host publicationProceedings
Subtitle of host publicationInternational Conference on Fibrous Products in Medical and Health Care, FiberMed11
EditorsPäivi Talvenmaa
Place of PublicationTampere
PublisherTampere University of Technology
ISBN (Print)978-952-15-2607-7
Publication statusPublished - 2011
MoE publication typeA4 Article in a conference publication
EventInternational conference on Fibrous Products in Medical and Health Care, FiberMed11 - Tampere, Finland
Duration: 28 Jun 201130 Jun 2011

Conference

ConferenceInternational conference on Fibrous Products in Medical and Health Care, FiberMed11
Abbreviated titleFiberMed11
CountryFinland
CityTampere
Period28/06/1130/06/11

Fingerprint

Papermaking
Fluidics
Antibodies
Wetting
Printing
Structural properties
Flow of fluids
Luminance
Cellulose
Health
Adsorption
Fluids
Fibers
Liquids
Costs

Cite this

Teerinen, T., Lappalainen, T., Vento, P., Hakalahti, L., & Erho, T. (2011). Printable paper-based diagnostics. In P. Talvenmaa (Ed.), Proceedings: International Conference on Fibrous Products in Medical and Health Care, FiberMed11 Tampere: Tampere University of Technology.
Teerinen, Tuija ; Lappalainen, Timo ; Vento, Pia ; Hakalahti, Leena ; Erho, Tomi. / Printable paper-based diagnostics. Proceedings: International Conference on Fibrous Products in Medical and Health Care, FiberMed11. editor / Päivi Talvenmaa. Tampere : Tampere University of Technology, 2011.
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title = "Printable paper-based diagnostics",
abstract = "We applied papermaking techniques to modify the structural properties of the cellulose fiber network in an attempt to design inexpensive, easy-to-use and disposable paper-based analytical devices. The ability of the paper to wick liquids by capillary action was exploited in the development of lateral flow test device. The paper grade was evaluated to meet the needs for sustainable flow of liquids, stability in wetting conditions, brightness and homogeneity. Biofunctionalization of the modified paper was achieved through inkjet printing methods. We show that it was possible to control the fluidic properties of paper to support the transport of fluids and detection particles, to immobilize antibodies on paper by simple physical adsorption and to detect the analyte in clinically relevant ranges. This research was conducted towards the development and design of paper-based diagnostics in the fields of health, well-being, veterinary and environmental point-of-care diagnostics, where the main focus is versatility, novel test formats and low-cost mass production.",
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Teerinen, T, Lappalainen, T, Vento, P, Hakalahti, L & Erho, T 2011, Printable paper-based diagnostics. in P Talvenmaa (ed.), Proceedings: International Conference on Fibrous Products in Medical and Health Care, FiberMed11. Tampere University of Technology, Tampere, International conference on Fibrous Products in Medical and Health Care, FiberMed11, Tampere, Finland, 28/06/11.

Printable paper-based diagnostics. / Teerinen, Tuija; Lappalainen, Timo; Vento, Pia; Hakalahti, Leena; Erho, Tomi.

Proceedings: International Conference on Fibrous Products in Medical and Health Care, FiberMed11. ed. / Päivi Talvenmaa. Tampere : Tampere University of Technology, 2011.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

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T1 - Printable paper-based diagnostics

AU - Teerinen, Tuija

AU - Lappalainen, Timo

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N2 - We applied papermaking techniques to modify the structural properties of the cellulose fiber network in an attempt to design inexpensive, easy-to-use and disposable paper-based analytical devices. The ability of the paper to wick liquids by capillary action was exploited in the development of lateral flow test device. The paper grade was evaluated to meet the needs for sustainable flow of liquids, stability in wetting conditions, brightness and homogeneity. Biofunctionalization of the modified paper was achieved through inkjet printing methods. We show that it was possible to control the fluidic properties of paper to support the transport of fluids and detection particles, to immobilize antibodies on paper by simple physical adsorption and to detect the analyte in clinically relevant ranges. This research was conducted towards the development and design of paper-based diagnostics in the fields of health, well-being, veterinary and environmental point-of-care diagnostics, where the main focus is versatility, novel test formats and low-cost mass production.

AB - We applied papermaking techniques to modify the structural properties of the cellulose fiber network in an attempt to design inexpensive, easy-to-use and disposable paper-based analytical devices. The ability of the paper to wick liquids by capillary action was exploited in the development of lateral flow test device. The paper grade was evaluated to meet the needs for sustainable flow of liquids, stability in wetting conditions, brightness and homogeneity. Biofunctionalization of the modified paper was achieved through inkjet printing methods. We show that it was possible to control the fluidic properties of paper to support the transport of fluids and detection particles, to immobilize antibodies on paper by simple physical adsorption and to detect the analyte in clinically relevant ranges. This research was conducted towards the development and design of paper-based diagnostics in the fields of health, well-being, veterinary and environmental point-of-care diagnostics, where the main focus is versatility, novel test formats and low-cost mass production.

M3 - Conference article in proceedings

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Teerinen T, Lappalainen T, Vento P, Hakalahti L, Erho T. Printable paper-based diagnostics. In Talvenmaa P, editor, Proceedings: International Conference on Fibrous Products in Medical and Health Care, FiberMed11. Tampere: Tampere University of Technology. 2011