Probing the red blood cell interaction in individual cell pairs by optical tweezers

Ruixue Zhu*, Alexey Popov, Igor Meglinski

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

1 Citation (Scopus)

Abstract

The peculiarity of red blood cell interaction was studied by optical tweezers. The intercellular interaction force in cell pairs and the role of cell deformation and adhesion time in interaction dynamics were evaluated and discussed.
Original languageEnglish
Title of host publicationCLEO: Applications and Technology 2020
Subtitle of host publicationConference on Lasers and Electro-Optics
PublisherOptica Publishing Group
ISBN (Electronic)978-1-943580-76-7
ISBN (Print)9781943580767
DOIs
Publication statusPublished - 2020
MoE publication typeA4 Article in a conference publication
EventCLEO Applications and Technology, CLEO_AT 2020: Online - Virtual, Washington, United States
Duration: 10 May 202015 May 2020

Publication series

SeriesOptics InfoBase Conference Papers
NumberF181-CLEO-AT 2020
ISSN2162-2701

Conference

ConferenceCLEO Applications and Technology, CLEO_AT 2020
Country/TerritoryUnited States
CityWashington
Period10/05/2015/05/20

Funding

The interaction between human RBCs in individual cell pairs was evaluated with double-beam OT. In RBC disaggregation measurement, the trapping force has to overcome both the cellular attracting force and RBC deformation force. The intercellular interaction between RBCs increases with cells mutual contact time. Our study improves the understanding of the dynamic interaction between RBCs in autologous plasma, and clarifies possible influence factors in the measurement with OT. The China Scholarship Council (CSC No. 201706410089, R.Z.) and Tauno Tönning Foundation (grant No. 20190104, R.Z.) are acknowledged for financial support.

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