Abstract
The peculiarity of red blood cell interaction was studied by optical tweezers. The intercellular interaction force in cell pairs and the role of cell deformation and adhesion time in interaction dynamics were evaluated and discussed.
| Original language | English |
|---|---|
| Title of host publication | CLEO: Applications and Technology 2020 |
| Subtitle of host publication | Conference on Lasers and Electro-Optics |
| Publisher | Optica Publishing Group |
| ISBN (Electronic) | 978-1-943580-76-7 |
| ISBN (Print) | 9781943580767 |
| DOIs | |
| Publication status | Published - 2020 |
| MoE publication type | A4 Article in a conference publication |
| Event | CLEO Applications and Technology, CLEO_AT 2020: Online - Virtual, Washington, United States Duration: 10 May 2020 → 15 May 2020 |
Publication series
| Series | Optics InfoBase Conference Papers |
|---|---|
| Number | F181-CLEO-AT 2020 |
| ISSN | 2162-2701 |
Conference
| Conference | CLEO Applications and Technology, CLEO_AT 2020 |
|---|---|
| Country/Territory | United States |
| City | Washington |
| Period | 10/05/20 → 15/05/20 |
Funding
The interaction between human RBCs in individual cell pairs was evaluated with double-beam OT. In RBC disaggregation measurement, the trapping force has to overcome both the cellular attracting force and RBC deformation force. The intercellular interaction between RBCs increases with cells mutual contact time. Our study improves the understanding of the dynamic interaction between RBCs in autologous plasma, and clarifies possible influence factors in the measurement with OT. The China Scholarship Council (CSC No. 201706410089, R.Z.) and Tauno Tönning Foundation (grant No. 20190104, R.Z.) are acknowledged for financial support.