Production and characterization of antibacterial compounds produced by Pediococcus damnosus and Pediococcus pentosaceus

Eija Skyttä (Corresponding Author), Auli Haikara, Tiina Mattila-Sandholm

Research output: Contribution to journalArticleScientificpeer-review

43 Citations (Scopus)

Abstract

The broad‐spectrum antibacterial activity exhibited by three Pediococcus strains isolated from beer was preliminarily characterized. Factors affecting the production rate of bacterial inhibitors were screened and the effects of simultaneous cultivation of Lactococcus and Pediococcus on the production of inhibitory substances were studied. The antibacterial activity against a range of Gram‐negative test organisms was not affected by catalase or proteolytic enzymes and was extremely thermotolerant. Production of the inhibitors was maximal between pH 6 and pH 7. A growth medium containing unhopped end‐fermented wort was beneficial for the production of inhibitors, particularly by the Pediococcus damnosus strain, and anaerobic growth conditions were preferable. The antagonistic activity against the Gram‐negative test organism Salmonella infantis could be demonstrated after an incubation period of only 2 d if the Pediococcus and Lactococcus strains were incubated simultaneously as a mixed population.

Original languageEnglish
Pages (from-to)134 - 142
Number of pages9
JournalJournal of Applied Bacteriology
Volume74
Issue number2
DOIs
Publication statusPublished - 1993
MoE publication typeA1 Journal article-refereed

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Pediococcus
Lactococcus
Growth
Salmonella
Catalase
Peptide Hydrolases
Pediococcus pentosaceus
Population

Cite this

Skyttä, Eija ; Haikara, Auli ; Mattila-Sandholm, Tiina. / Production and characterization of antibacterial compounds produced by Pediococcus damnosus and Pediococcus pentosaceus. In: Journal of Applied Bacteriology. 1993 ; Vol. 74, No. 2. pp. 134 - 142.
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Production and characterization of antibacterial compounds produced by Pediococcus damnosus and Pediococcus pentosaceus. / Skyttä, Eija (Corresponding Author); Haikara, Auli; Mattila-Sandholm, Tiina.

In: Journal of Applied Bacteriology, Vol. 74, No. 2, 1993, p. 134 - 142.

Research output: Contribution to journalArticleScientificpeer-review

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T1 - Production and characterization of antibacterial compounds produced by Pediococcus damnosus and Pediococcus pentosaceus

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