TY - JOUR
T1 - Production of novel chia-mucilage nanocomposite films with starch nanocrystals; An inclusive biological and physicochemical perspective
AU - Mujtaba, Muhammad
AU - Koc, Behlul
AU - Salaberria, Asier Martinez
AU - Ilk, Sedef
AU - Cansaran-Duman, Demet
AU - Akyuz, Lalehan
AU - Cakmak, Yavuz Selim
AU - Kaya, Murat
AU - Khawar, Khalid Mahmood
AU - Labidi, Jalel
AU - Boufi, Sami
N1 - Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2019/7/15
Y1 - 2019/7/15
N2 - In the current study, chia mucilage composite films with starch nanocrystals (3% and 6%)were produced. The films were analyzed physicochemically (FT-IR, AFM, TGA, DSC), mechanically (Tensile strength and contact angle)and biologically (antimicrobial, antioxidant and cytotoxicity)properties. The incorporation of starch nanocrystals was confirmed through FT-IR spectra showing broad OH peak and C[dbnd]O stretching and shift in N[sbnd]H bending vibrations to the lower wave number. Starch nanocrystals enhanced (control 287.23 °C, film with 3% SNC 286.91 °C and film with 6% mucilage 289.41 °C)the thermal properties of the composite films. The Young Modulus of the film showed an increase after the incorporation of starch nanocrystals due to the strong interaction between mucilage and nanocrystals. On the other hand, the overall hydrophobicity of mucilage composite film decreased due to the hydrophilic nature of cornstarch nanocrystals. MTT assay for cell proliferation revealed significant inhibition of cancer cell (HepG2)lines and exhibits a very low inhibition of epithelial cell line (Vero). Starch nanocrystals enhanced the antibacterial and antioxidant (threefold increase compare to control)properties of mucilage composite films. Mucilage-SNC composite films could be a good therapeutic gain for control and directed drug delivery, food packaging, food coating.
AB - In the current study, chia mucilage composite films with starch nanocrystals (3% and 6%)were produced. The films were analyzed physicochemically (FT-IR, AFM, TGA, DSC), mechanically (Tensile strength and contact angle)and biologically (antimicrobial, antioxidant and cytotoxicity)properties. The incorporation of starch nanocrystals was confirmed through FT-IR spectra showing broad OH peak and C[dbnd]O stretching and shift in N[sbnd]H bending vibrations to the lower wave number. Starch nanocrystals enhanced (control 287.23 °C, film with 3% SNC 286.91 °C and film with 6% mucilage 289.41 °C)the thermal properties of the composite films. The Young Modulus of the film showed an increase after the incorporation of starch nanocrystals due to the strong interaction between mucilage and nanocrystals. On the other hand, the overall hydrophobicity of mucilage composite film decreased due to the hydrophilic nature of cornstarch nanocrystals. MTT assay for cell proliferation revealed significant inhibition of cancer cell (HepG2)lines and exhibits a very low inhibition of epithelial cell line (Vero). Starch nanocrystals enhanced the antibacterial and antioxidant (threefold increase compare to control)properties of mucilage composite films. Mucilage-SNC composite films could be a good therapeutic gain for control and directed drug delivery, food packaging, food coating.
KW - Antimicrobial
KW - Antioxidant
KW - Mucilage film
UR - http://www.scopus.com/inward/record.url?scp=85064627092&partnerID=8YFLogxK
U2 - 10.1016/j.ijbiomac.2019.04.146
DO - 10.1016/j.ijbiomac.2019.04.146
M3 - Article
C2 - 31022490
AN - SCOPUS:85064627092
SN - 0141-8130
VL - 133
SP - 663
EP - 673
JO - International Journal of Biological Macromolecules
JF - International Journal of Biological Macromolecules
ER -
