Regulation of tropane alkaloid metabolism in plants and plant cell cultures

    Research output: Chapter in Book/Report/Conference proceedingChapter or book articleScientificpeer-review


    Tropane alkaloids are among the oldest drugs in medicine. Besides the medicinal use they possess hallucinogenic and poisonous properties. Many plants belonging to the Solanaceae family have been used for centuries because of their active principles, hyoscyamine and scopolamine. The name hyoscyamine is derived from Hyoscyamus niger from which these two tropane alkaloids also for the first time were isolated.1,2 Later on Dunstan and Brown3 detected hyoscyamine in H. muticus. Also other Solanaceous plants belonging to Atropa, Datura, Duboisia and Scopolia produce these valuable alkaloids.
    Original languageEnglish
    Title of host publicationMetabolic Engineering of Plant Secondary Metabolism
    EditorsRobert Verpoorte, A. Wilhelm Alfermann
    Place of PublicationDordrecht
    ISBN (Electronic)978-94-015-9423-3, 978-90-481-5475-3
    ISBN (Print)978-0-7923-6360-6
    Publication statusPublished - 2000
    MoE publication typeA3 Part of a book or another research book


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