Tropane alkaloids are among the oldest drugs in medicine. Besides the medicinal use they possess hallucinogenic and poisonous properties. Many plants belonging to the Solanaceae family have been used for centuries because of their active principles, hyoscyamine and scopolamine. The name hyoscyamine is derived from Hyoscyamus niger from which these two tropane alkaloids also for the first time were isolated.1,2 Later on Dunstan and Brown3 detected hyoscyamine in H. muticus. Also other Solanaceous plants belonging to Atropa, Datura, Duboisia and Scopolia produce these valuable alkaloids.
|Title of host publication||Metabolic Engineering of Plant Secondary Metabolism|
|Editors||Robert Verpoorte, A. Wilhelm Alfermann|
|Place of Publication||Dordrecht|
|ISBN (Electronic)||978-94-015-9423-3, 978-90-481-5475-3|
|Publication status||Published - 2000|
|MoE publication type||A3 Part of a book or another research book|