SensApp: A FET-Open project for developing a supersensor able to detect Alzheimer's disease biomarkers in blood

Romina Rega, Martina Mugnano, Danila Del Giudice, Simona Itri, Volodymyr Tkachenko, Veronica Vespini, Sara Coppola, Pietro Ferraro, Heidi Ottevaere, Yunfeng Nie, Sanna Uusitalo, Reinhard Schwoediauer, Martin Kaltenbrunner, Markku Känsäkoski, Emanuela Mazzon, Pier Luca Maffettone, Gaetano D'Avino, Simonetta Grilli

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

Abstract

The goal of the SensApp FET-Open project is to develop an innovative super-sensor that will be able to detect Alzheimer's disease (AD) biomarkers (β-amyloid, Tau and pTAU) in peripheral blood. Considering that nowadays an accurate diagnosis of AD requires the highly invasive withdrawal and analysis of cerebrospinal fluid, SensApp will represent a breakthrough in the field of AD diagnosis thanks to the ability to detect the early stage of the disease by a simple blood collection. We call Droplet-Split-and-Stack (DSS) the new technology that will emerge from SensApp. The achievement of SensApp goal is enabled by the interdisciplinary cooperation between different research institutions and one company involved in the key fields of the project, Vrije Universiteit Brussels, VTT Technical Research Centre of Finland, University of Linz, Ginolis Ltd, IRCCS Centre “Bonino Pulejo”, under the coordination of CNR-Institute of Applied Sciences and Intelligent Systems. This communication will illustrate the progress of the activities.

Original languageEnglish
Title of host publicationOptical Methods for Inspection, Characterization, and Imaging of Biomaterials V
EditorsPietro Ferraro, Simonetta Grilli, Monika Ritsch-Marte, Christoph K. Hitzenberger
PublisherInternational Society for Optics and Photonics SPIE
ISBN (Electronic)978-1-5106-4406-9
DOIs
Publication statusPublished - 2021
MoE publication typeA4 Article in a conference publication
EventOptical Methods for Inspection, Characterization, and Imaging of Biomaterials V 2021 - Virtual, Online, Germany
Duration: 21 Jun 202125 Jun 2021

Publication series

SeriesProceedings of SPIE - The International Society for Optical Engineering
Volume11786
ISSN0277-786X

Conference

ConferenceOptical Methods for Inspection, Characterization, and Imaging of Biomaterials V 2021
Country/TerritoryGermany
CityVirtual, Online
Period21/06/2125/06/21

Keywords

  • Alzheimer disease
  • Biosensors
  • Droplet-Spilt-and-Stack
  • SensApp project

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