Sensing an aqueous Intralipid suspension with optical coherence tomography; reconstruction of the scattering coefficients

Noura Ayari, Alexey Popov, Matti Kinnunen, Risto Myllylä, Zhang Fengsheng

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

3 Citations (Scopus)

Abstract

The working principle of optical coherence tomography (OCT) makes it possible to detect backscattered photons as a function of depth. The OCT signal includes single and least-scattered photons as well as multiple-scattered photons, and provides a logarithmic depth profile of coherently backscattered light in an OCT image. Single and least-scattered photons contribute to the information part of the OCT signal, while multiple-scattered photons mainly decrease the resolution. When the OCT signal is analyzed, rapid attenuation of the signal in a scattering medium is observed. Based on an exponential decay approximation that fits the OCT profile and the results of Monte Carlo simulations, it was possible to reconstruct the scattering coefficient μs for some concentrations of Intralipid water suspension. The case of single scattering was considered for 0.5 %, 1 %, 1.5 % and 2 % Intralipid. The reconstruction led to results very close to the theoretical values of the μs. For higher concentrations (9 % and 10 %), the reconstructed values were larger than the theoretical ones.

Original languageEnglish
Title of host publicationSaratov Fall Meeting 2006
Subtitle of host publicationCoherent Optics of Ordered and Random Media VII
EditorsDmitry A. Zimnyakov, Nikolai G. Khlebtsov
PublisherInternational Society for Optics and Photonics SPIE
ISBN (Print)978-0-8194-6658-7
DOIs
Publication statusPublished - 5 Nov 2007
MoE publication typeA4 Article in a conference publication
EventSaratov Fall Meeting 2006: Coherent Optics of Ordered and Random Media VII - Saratov, Russian Federation
Duration: 26 Sep 200630 Sep 2006

Publication series

SeriesProceedings of SPIE
Volume6536
ISSN0277-786X

Conference

ConferenceSaratov Fall Meeting 2006
CountryRussian Federation
CitySaratov
Period26/09/0630/09/06

Keywords

  • Intralipid
  • Monte Carlo simulation
  • Optical coherence tomography
  • Reconstruction of scattering parameters
  • Scattering coefficient

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