Single sweep analysis of event related auditory potentials for the monitoring of sedation in cardiac surgery patients

Luca Mainardi; Jukka Kupila; Kari Nieminen; Ilkka Korhonen; Anna Bianchi; Linda Pattini; Jukka Takala; Jari Karhu; Sergio Cerutti

doi:10.1016/S0169-2607(00)00112-7

Single sweep analysis of event related auditory potentials for the monitoring of sedation in cardiac surgery patients

Luca Mainardi (Corresponding Author), Jukka Kupila, Kari Nieminen, Ilkka Korhonen, Anna Bianchi, Linda Pattini, Jukka Takala, Jari Karhu, Sergio Cerutti

VTT Technical Research Centre of Finland

Research output: Contribution to journal › Article › Scientific › peer-review

13 Citations (Scopus)

Abstract

Event-related potentials (ERPs) from the auditory system were investigated in 28 post-operative cardiac patients in order to assess their relevance in the monitoring of patient sedation level. Midazolam (17 patients) and propofol (11 patients) were the sedative agents used. The auditory ERP components of N100 (HAB100) and mismatch negativity (MMN) were considered. A single sweep method based on the AutoRegressive with eXogenous input (ARX) model, which is able to enhance the evoked responses to each single stimulus, was used to process each sweep and to compute traditional parameters on a sweep-by-sweep basis. Differences in the measured parameters were related to variations in the patient sedation levels classified through Ramsay score. Significant differences (P<0.05) in both MMN and HAB100 parameters were found between light sedation (LS) and deep sedation (DS) levels.

Original language	English
Pages (from-to)	219-227
Journal	Computer Methods and Programs in Biomedicine
Volume	63
Issue number	3
DOIs	https://doi.org/10.1016/S0169-2607(00)00112-7
Publication status	Published - 2000
MoE publication type	A1 Journal article-refereed

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title = "Single sweep analysis of event related auditory potentials for the monitoring of sedation in cardiac surgery patients",

abstract = "Event-related potentials (ERPs) from the auditory system were investigated in 28 post-operative cardiac patients in order to assess their relevance in the monitoring of patient sedation level. Midazolam (17 patients) and propofol (11 patients) were the sedative agents used. The auditory ERP components of N100 (HAB100) and mismatch negativity (MMN) were considered. A single sweep method based on the AutoRegressive with eXogenous input (ARX) model, which is able to enhance the evoked responses to each single stimulus, was used to process each sweep and to compute traditional parameters on a sweep-by-sweep basis. Differences in the measured parameters were related to variations in the patient sedation levels classified through Ramsay score. Significant differences (P<0.05) in both MMN and HAB100 parameters were found between light sedation (LS) and deep sedation (DS) levels.",

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doi = "10.1016/S0169-2607(00)00112-7",

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T1 - Single sweep analysis of event related auditory potentials for the monitoring of sedation in cardiac surgery patients

AU - Mainardi, Luca

AU - Kupila, Jukka

AU - Nieminen, Kari

AU - Korhonen, Ilkka

AU - Bianchi, Anna

AU - Pattini, Linda

AU - Takala, Jukka

AU - Karhu, Jari

AU - Cerutti, Sergio

PY - 2000

Y1 - 2000

N2 - Event-related potentials (ERPs) from the auditory system were investigated in 28 post-operative cardiac patients in order to assess their relevance in the monitoring of patient sedation level. Midazolam (17 patients) and propofol (11 patients) were the sedative agents used. The auditory ERP components of N100 (HAB100) and mismatch negativity (MMN) were considered. A single sweep method based on the AutoRegressive with eXogenous input (ARX) model, which is able to enhance the evoked responses to each single stimulus, was used to process each sweep and to compute traditional parameters on a sweep-by-sweep basis. Differences in the measured parameters were related to variations in the patient sedation levels classified through Ramsay score. Significant differences (P<0.05) in both MMN and HAB100 parameters were found between light sedation (LS) and deep sedation (DS) levels.

AB - Event-related potentials (ERPs) from the auditory system were investigated in 28 post-operative cardiac patients in order to assess their relevance in the monitoring of patient sedation level. Midazolam (17 patients) and propofol (11 patients) were the sedative agents used. The auditory ERP components of N100 (HAB100) and mismatch negativity (MMN) were considered. A single sweep method based on the AutoRegressive with eXogenous input (ARX) model, which is able to enhance the evoked responses to each single stimulus, was used to process each sweep and to compute traditional parameters on a sweep-by-sweep basis. Differences in the measured parameters were related to variations in the patient sedation levels classified through Ramsay score. Significant differences (P<0.05) in both MMN and HAB100 parameters were found between light sedation (LS) and deep sedation (DS) levels.

U2 - 10.1016/S0169-2607(00)00112-7

DO - 10.1016/S0169-2607(00)00112-7

M3 - Article

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VL - 63

SP - 219

EP - 227

JO - Computer Methods and Programs in Biomedicine

JF - Computer Methods and Programs in Biomedicine

IS - 3

ER -

Single sweep analysis of event related auditory potentials for the monitoring of sedation in cardiac surgery patients

Abstract

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