Structural homology among the peroxidase enzyme family revealed by hydrophobic cluster analysis

Bernard Henrissat, Markku Saloheimo, Stephanie Lavaitte, Jonathan Knowles

Research output: Contribution to journalArticleScientificpeer-review

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Abstract

A number of peroxidase amino acid sequences show limited homology to short regions comprising the known active site cleft of yeast cytochrome c peroxidase. Otherwise no clear homology is visible in linear alignments between this enzyme and other peroxidases. We have subjected eight peroxidase sequences to hydrophobic cluster analysis. Our results suggest that these peroxidases are evolutionary related and that they share many folding characteristics.
Original languageEnglish
Pages (from-to)251-257
JournalProteins
Volume8
Issue number3
DOIs
Publication statusPublished - 1990
MoE publication typeA1 Journal article-refereed

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Peroxidases
Cluster analysis
Peroxidase
Cluster Analysis
Cytochrome-c Peroxidase
Enzymes
Yeast
Amino Acid Sequence
Catalytic Domain
Yeasts
Amino Acids

Cite this

Henrissat, Bernard ; Saloheimo, Markku ; Lavaitte, Stephanie ; Knowles, Jonathan. / Structural homology among the peroxidase enzyme family revealed by hydrophobic cluster analysis. In: Proteins. 1990 ; Vol. 8, No. 3. pp. 251-257.
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abstract = "A number of peroxidase amino acid sequences show limited homology to short regions comprising the known active site cleft of yeast cytochrome c peroxidase. Otherwise no clear homology is visible in linear alignments between this enzyme and other peroxidases. We have subjected eight peroxidase sequences to hydrophobic cluster analysis. Our results suggest that these peroxidases are evolutionary related and that they share many folding characteristics.",
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Structural homology among the peroxidase enzyme family revealed by hydrophobic cluster analysis. / Henrissat, Bernard; Saloheimo, Markku; Lavaitte, Stephanie; Knowles, Jonathan.

In: Proteins, Vol. 8, No. 3, 1990, p. 251-257.

Research output: Contribution to journalArticleScientificpeer-review

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AU - Saloheimo, Markku

AU - Lavaitte, Stephanie

AU - Knowles, Jonathan

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AB - A number of peroxidase amino acid sequences show limited homology to short regions comprising the known active site cleft of yeast cytochrome c peroxidase. Otherwise no clear homology is visible in linear alignments between this enzyme and other peroxidases. We have subjected eight peroxidase sequences to hydrophobic cluster analysis. Our results suggest that these peroxidases are evolutionary related and that they share many folding characteristics.

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