Study of continuous two-dimensional thermal field-flow fractionation of polymers

Pertti Vastamäki, Matti Jussila, Marja-Liisa Riekkola (Corresponding Author)

Research output: Contribution to journalArticleScientificpeer-review

3 Citations (Scopus)

Abstract

Two-dimensional thermal field-flow fractionation (2D-ThFFF) is a new instrumental technique devised for continuous fractionation of soluble macromolecules and particles. The sample mixture is introduced into a disc-shaped channel and the separated sample components are collected continuously from the channel outlets. The method is based on a two-dimensional fractionation mechanism with radial and tangential flow components in the channel. The effects of flow components and thermal gradient on the fractionation were studied in the separation of polystyrene samples of different molecular masses using cyclohexane or a binary solvent consisting of 25% ethylbenzene and 75% cyclohexane as carrier. The continuous separation of polystyrene samples was improved with increasing thermal gradient and with the use of slow radial and tangential flow rates. The technique can be applied to preparative continuous separation of macromolecules.
Original languageEnglish
Pages (from-to)1243-1248
JournalThe Analyst
Volume128
Issue number10
DOIs
Publication statusPublished - 2003
MoE publication typeA1 Journal article-refereed

Fingerprint

Field Flow Fractionation
Fractionation
flow field
Flow fields
Polymers
fractionation
polymer
Hot Temperature
Polystyrenes
Cyclohexane
Macromolecules
Thermal gradients
Ethylbenzene
Molecular mass
Flow rate

Cite this

Vastamäki, Pertti ; Jussila, Matti ; Riekkola, Marja-Liisa. / Study of continuous two-dimensional thermal field-flow fractionation of polymers. In: The Analyst. 2003 ; Vol. 128, No. 10. pp. 1243-1248.
@article{7327096286e04f53afdf8a3b232e1b94,
title = "Study of continuous two-dimensional thermal field-flow fractionation of polymers",
abstract = "Two-dimensional thermal field-flow fractionation (2D-ThFFF) is a new instrumental technique devised for continuous fractionation of soluble macromolecules and particles. The sample mixture is introduced into a disc-shaped channel and the separated sample components are collected continuously from the channel outlets. The method is based on a two-dimensional fractionation mechanism with radial and tangential flow components in the channel. The effects of flow components and thermal gradient on the fractionation were studied in the separation of polystyrene samples of different molecular masses using cyclohexane or a binary solvent consisting of 25{\%} ethylbenzene and 75{\%} cyclohexane as carrier. The continuous separation of polystyrene samples was improved with increasing thermal gradient and with the use of slow radial and tangential flow rates. The technique can be applied to preparative continuous separation of macromolecules.",
author = "Pertti Vastam{\"a}ki and Matti Jussila and Marja-Liisa Riekkola",
year = "2003",
doi = "10.1039/B307292B",
language = "English",
volume = "128",
pages = "1243--1248",
journal = "The Analyst",
issn = "0003-2654",
publisher = "Royal Society of Chemistry RSC",
number = "10",

}

Study of continuous two-dimensional thermal field-flow fractionation of polymers. / Vastamäki, Pertti; Jussila, Matti; Riekkola, Marja-Liisa (Corresponding Author).

In: The Analyst, Vol. 128, No. 10, 2003, p. 1243-1248.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Study of continuous two-dimensional thermal field-flow fractionation of polymers

AU - Vastamäki, Pertti

AU - Jussila, Matti

AU - Riekkola, Marja-Liisa

PY - 2003

Y1 - 2003

N2 - Two-dimensional thermal field-flow fractionation (2D-ThFFF) is a new instrumental technique devised for continuous fractionation of soluble macromolecules and particles. The sample mixture is introduced into a disc-shaped channel and the separated sample components are collected continuously from the channel outlets. The method is based on a two-dimensional fractionation mechanism with radial and tangential flow components in the channel. The effects of flow components and thermal gradient on the fractionation were studied in the separation of polystyrene samples of different molecular masses using cyclohexane or a binary solvent consisting of 25% ethylbenzene and 75% cyclohexane as carrier. The continuous separation of polystyrene samples was improved with increasing thermal gradient and with the use of slow radial and tangential flow rates. The technique can be applied to preparative continuous separation of macromolecules.

AB - Two-dimensional thermal field-flow fractionation (2D-ThFFF) is a new instrumental technique devised for continuous fractionation of soluble macromolecules and particles. The sample mixture is introduced into a disc-shaped channel and the separated sample components are collected continuously from the channel outlets. The method is based on a two-dimensional fractionation mechanism with radial and tangential flow components in the channel. The effects of flow components and thermal gradient on the fractionation were studied in the separation of polystyrene samples of different molecular masses using cyclohexane or a binary solvent consisting of 25% ethylbenzene and 75% cyclohexane as carrier. The continuous separation of polystyrene samples was improved with increasing thermal gradient and with the use of slow radial and tangential flow rates. The technique can be applied to preparative continuous separation of macromolecules.

U2 - 10.1039/B307292B

DO - 10.1039/B307292B

M3 - Article

VL - 128

SP - 1243

EP - 1248

JO - The Analyst

JF - The Analyst

SN - 0003-2654

IS - 10

ER -