Study of the relative dose-response of BANG-3® polymer gel dosimeters in epithermal neutron irradiation

J. Uusi-Simola, S. Savolainen, A. Kangasmäki, S. Heikkinen, J. Perkiö, U. Abo Ramadan, T. Seppälä, J. Karila, T. Serén, P. Kotiluoto, P. Sorvari, I. Auterinen

Research output: Contribution to journalArticleScientificpeer-review

22 Citations (Scopus)

Abstract

Polymer gels have been reported as a new, potential tool for dosimetry in mixed neutron-gamma radiation fields. In this work, BANG-3 (MGS Research Inc.) gel vials from three production batches were irradiated with 6 MV photons of a Varian Clinac 2100 C linear accelerator and with the epithermal neutron beam of the Finnish boron neutron capture therapy (BNCT) facility at the FiR 1 nuclear reactor. The gel is tissue equivalent in main elemental composition and density and its T2 relaxation time is dependent on the absorbed dose. The T2 relaxation time map of the irradiated gel vials was measured with a 1.5 T magnetic resonance (MR) scanner using spin echo sequence. The absorbed doses of neutron irradiation were calculated using DORT computer code, and the accuracy of the calculational model was verified by measuring gamma ray dose rate with thermoluminescent dosimeters and 55Mn(n,γ) activation reaction rate with activation detectors. The response of the BANG-3 gel dosimeter for total absorbed dose in the neutron irradiation was linear, and the magnitude of the response relative to the response in the photon irradiation was observed to vary between different gel batches. The results support the potential of polymer gels in BNCT dosimetry, especially for the verification of two- or three-dimensional dose distributions.

Original languageEnglish
Pages (from-to)2895-2906
Number of pages12
JournalPhysics in Medicine and Biology
Volume48
Issue number17
DOIs
Publication statusPublished - 7 Sep 2003
MoE publication typeA1 Journal article-refereed

Fingerprint

Dosimeters
Neutron irradiation
Neutrons
neutron irradiation
Dosimetry
dosimeters
Gels
gels
dosage
polymers
Polymers
Boron Neutron Capture Therapy
Gamma Rays
Photons
neutrons
Gamma rays
Relaxation time
Boron
therapy
boron

Keywords

  • dosimetry
  • gel dosimeter
  • epithermal irradiation
  • epithermal neutrons
  • boron neutron capture therapy

Cite this

Uusi-Simola, J. ; Savolainen, S. ; Kangasmäki, A. ; Heikkinen, S. ; Perkiö, J. ; Abo Ramadan, U. ; Seppälä, T. ; Karila, J. ; Serén, T. ; Kotiluoto, P. ; Sorvari, P. ; Auterinen, I. / Study of the relative dose-response of BANG-3® polymer gel dosimeters in epithermal neutron irradiation. In: Physics in Medicine and Biology. 2003 ; Vol. 48, No. 17. pp. 2895-2906.
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abstract = "Polymer gels have been reported as a new, potential tool for dosimetry in mixed neutron-gamma radiation fields. In this work, BANG-3 (MGS Research Inc.) gel vials from three production batches were irradiated with 6 MV photons of a Varian Clinac 2100 C linear accelerator and with the epithermal neutron beam of the Finnish boron neutron capture therapy (BNCT) facility at the FiR 1 nuclear reactor. The gel is tissue equivalent in main elemental composition and density and its T2 relaxation time is dependent on the absorbed dose. The T2 relaxation time map of the irradiated gel vials was measured with a 1.5 T magnetic resonance (MR) scanner using spin echo sequence. The absorbed doses of neutron irradiation were calculated using DORT computer code, and the accuracy of the calculational model was verified by measuring gamma ray dose rate with thermoluminescent dosimeters and 55Mn(n,γ) activation reaction rate with activation detectors. The response of the BANG-3 gel dosimeter for total absorbed dose in the neutron irradiation was linear, and the magnitude of the response relative to the response in the photon irradiation was observed to vary between different gel batches. The results support the potential of polymer gels in BNCT dosimetry, especially for the verification of two- or three-dimensional dose distributions.",
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Uusi-Simola, J, Savolainen, S, Kangasmäki, A, Heikkinen, S, Perkiö, J, Abo Ramadan, U, Seppälä, T, Karila, J, Serén, T, Kotiluoto, P, Sorvari, P & Auterinen, I 2003, 'Study of the relative dose-response of BANG-3® polymer gel dosimeters in epithermal neutron irradiation', Physics in Medicine and Biology, vol. 48, no. 17, pp. 2895-2906. https://doi.org/10.1088/0031-9155/48/17/310

Study of the relative dose-response of BANG-3® polymer gel dosimeters in epithermal neutron irradiation. / Uusi-Simola, J.; Savolainen, S.; Kangasmäki, A.; Heikkinen, S.; Perkiö, J.; Abo Ramadan, U.; Seppälä, T.; Karila, J.; Serén, T.; Kotiluoto, P.; Sorvari, P.; Auterinen, I.

In: Physics in Medicine and Biology, Vol. 48, No. 17, 07.09.2003, p. 2895-2906.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Study of the relative dose-response of BANG-3® polymer gel dosimeters in epithermal neutron irradiation

AU - Uusi-Simola, J.

AU - Savolainen, S.

AU - Kangasmäki, A.

AU - Heikkinen, S.

AU - Perkiö, J.

AU - Abo Ramadan, U.

AU - Seppälä, T.

AU - Karila, J.

AU - Serén, T.

AU - Kotiluoto, P.

AU - Sorvari, P.

AU - Auterinen, I.

PY - 2003/9/7

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N2 - Polymer gels have been reported as a new, potential tool for dosimetry in mixed neutron-gamma radiation fields. In this work, BANG-3 (MGS Research Inc.) gel vials from three production batches were irradiated with 6 MV photons of a Varian Clinac 2100 C linear accelerator and with the epithermal neutron beam of the Finnish boron neutron capture therapy (BNCT) facility at the FiR 1 nuclear reactor. The gel is tissue equivalent in main elemental composition and density and its T2 relaxation time is dependent on the absorbed dose. The T2 relaxation time map of the irradiated gel vials was measured with a 1.5 T magnetic resonance (MR) scanner using spin echo sequence. The absorbed doses of neutron irradiation were calculated using DORT computer code, and the accuracy of the calculational model was verified by measuring gamma ray dose rate with thermoluminescent dosimeters and 55Mn(n,γ) activation reaction rate with activation detectors. The response of the BANG-3 gel dosimeter for total absorbed dose in the neutron irradiation was linear, and the magnitude of the response relative to the response in the photon irradiation was observed to vary between different gel batches. The results support the potential of polymer gels in BNCT dosimetry, especially for the verification of two- or three-dimensional dose distributions.

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KW - dosimetry

KW - gel dosimeter

KW - epithermal irradiation

KW - epithermal neutrons

KW - boron neutron capture therapy

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U2 - 10.1088/0031-9155/48/17/310

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Uusi-Simola J, Savolainen S, Kangasmäki A, Heikkinen S, Perkiö J, Abo Ramadan U et al. Study of the relative dose-response of BANG-3® polymer gel dosimeters in epithermal neutron irradiation. Physics in Medicine and Biology. 2003 Sep 7;48(17):2895-2906. https://doi.org/10.1088/0031-9155/48/17/310