13C metabolic flux profiling of Pichia pastoris grown in aerobic batch cultures on glucose revealed high relative anabolic use of TCA cycle and limited incorporation of provided precursors of branched-chain amino acids

Meng Zhang, Xiao-Wei Yu, Yan Xu, Paula Jouhten, Gurla V.T. Swapna, Ralf W. Glaser, John F. Hunt, Gaetano T. Montelione, Hannu Maaheimo, Thomas Szyperski

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Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology