Susceptibility of bifidobacteria originating from different sources to tetracycline, erythromycin, streptomycin and vancomycin

Maria Saarela (Corresponding Author), S. Mayrhofer, K. J. Domig, M. Danielsen, B. Mayo, Jaana Mättö

Research output: Contribution to journalArticleScientificpeer-review

2 Citations (Scopus)

Abstract

MIC distributions of 365 Bifidobacterium spp. strains were determined for tetracycline, erythromycin,streptomycin and vancomycin. Susceptibility testing was performed either by Etest or broth microdilution (MDIL) using VetMIC panels. The tetracycline susceptible wild type population isolates of the human/probiotic Bifidobacterium spp., tested b Etest, had MICs ≤1μg/ml (B. adolescentis group, B. bifidum, B. catenulatum) or ≤ 4 μg/ml (B. longum group). All tetracycline susceptible wild type populations of the animal bifidobacteria, tested by broth microdilution, had MICs ≤ 4 μg/ml (B.pseudolongum) or ≤ 8 μg/ml (B. thermophilum). Acquired resistance to erythromycin was rare in bifidobacteria. B. adolescentis group, B. bifidum and B. pseudolongum showed a unimodal distribution consisting of only susceptible wild type population (cut-offs ≤ 0.25 μg/ml, ≤ 0.12 μg/ml, and ≤ 0.5 μg/ml, respectively). Eleven potentially erythromycin resistant strains representing B. animalis, B. longum group, B. catenulatum group and B. thermophilum were detected (cut-off for the groups being ≤ 0.25 μg/ml, ≤ 0.25 μg/ml, ≤ 0.25 μg/ml, and ≤ 1 μg/ml, respectively). All studied Bifidobacterium species/groups were intrinsically resistant to streptomycin and susceptible to vancomycin (cut-offs for B. adolescentis group, B. catenulatum group, B. animalis strains being ≤ 1 μg/ml, for B. longum group and B. bifidum ≤ 2 μg/ml, and for B. thermophilum, B.pseudolongum ≤ 1 μg/ml vancomycin).
Original languageEnglish
Pages (from-to)269-270
Number of pages2
JournalInternational Journal of Probiotics and Prebiotics
Volume3
Issue number4
Publication statusPublished - 2008
MoE publication typeA1 Journal article-refereed

Fingerprint

Bifidobacterium
vancomycin
erythromycin
Streptomycin
Erythromycin
Vancomycin
streptomycin
Tetracycline
tetracycline
Bifidobacterium catenulatum
Disk Diffusion Antimicrobial Tests
Bifidobacterium adolescentis
Population
Bifidobacterium bifidum
Bifidobacterium longum
Bifidobacterium animalis
Wild Animals
Probiotics
probiotics
animals

Keywords

  • Bifidobacterium
  • tetracycline
  • erythromycin
  • streptomycin
  • vancomycin

Cite this

Saarela, Maria ; Mayrhofer, S. ; Domig, K. J. ; Danielsen, M. ; Mayo, B. ; Mättö, Jaana. / Susceptibility of bifidobacteria originating from different sources to tetracycline, erythromycin, streptomycin and vancomycin. In: International Journal of Probiotics and Prebiotics. 2008 ; Vol. 3, No. 4. pp. 269-270.
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Susceptibility of bifidobacteria originating from different sources to tetracycline, erythromycin, streptomycin and vancomycin. / Saarela, Maria (Corresponding Author); Mayrhofer, S.; Domig, K. J.; Danielsen, M.; Mayo, B.; Mättö, Jaana.

In: International Journal of Probiotics and Prebiotics, Vol. 3, No. 4, 2008, p. 269-270.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Susceptibility of bifidobacteria originating from different sources to tetracycline, erythromycin, streptomycin and vancomycin

AU - Saarela, Maria

AU - Mayrhofer, S.

AU - Domig, K. J.

AU - Danielsen, M.

AU - Mayo, B.

AU - Mättö, Jaana

PY - 2008

Y1 - 2008

N2 - MIC distributions of 365 Bifidobacterium spp. strains were determined for tetracycline, erythromycin,streptomycin and vancomycin. Susceptibility testing was performed either by Etest or broth microdilution (MDIL) using VetMIC panels. The tetracycline susceptible wild type population isolates of the human/probiotic Bifidobacterium spp., tested b Etest, had MICs ≤1μg/ml (B. adolescentis group, B. bifidum, B. catenulatum) or ≤ 4 μg/ml (B. longum group). All tetracycline susceptible wild type populations of the animal bifidobacteria, tested by broth microdilution, had MICs ≤ 4 μg/ml (B.pseudolongum) or ≤ 8 μg/ml (B. thermophilum). Acquired resistance to erythromycin was rare in bifidobacteria. B. adolescentis group, B. bifidum and B. pseudolongum showed a unimodal distribution consisting of only susceptible wild type population (cut-offs ≤ 0.25 μg/ml, ≤ 0.12 μg/ml, and ≤ 0.5 μg/ml, respectively). Eleven potentially erythromycin resistant strains representing B. animalis, B. longum group, B. catenulatum group and B. thermophilum were detected (cut-off for the groups being ≤ 0.25 μg/ml, ≤ 0.25 μg/ml, ≤ 0.25 μg/ml, and ≤ 1 μg/ml, respectively). All studied Bifidobacterium species/groups were intrinsically resistant to streptomycin and susceptible to vancomycin (cut-offs for B. adolescentis group, B. catenulatum group, B. animalis strains being ≤ 1 μg/ml, for B. longum group and B. bifidum ≤ 2 μg/ml, and for B. thermophilum, B.pseudolongum ≤ 1 μg/ml vancomycin).

AB - MIC distributions of 365 Bifidobacterium spp. strains were determined for tetracycline, erythromycin,streptomycin and vancomycin. Susceptibility testing was performed either by Etest or broth microdilution (MDIL) using VetMIC panels. The tetracycline susceptible wild type population isolates of the human/probiotic Bifidobacterium spp., tested b Etest, had MICs ≤1μg/ml (B. adolescentis group, B. bifidum, B. catenulatum) or ≤ 4 μg/ml (B. longum group). All tetracycline susceptible wild type populations of the animal bifidobacteria, tested by broth microdilution, had MICs ≤ 4 μg/ml (B.pseudolongum) or ≤ 8 μg/ml (B. thermophilum). Acquired resistance to erythromycin was rare in bifidobacteria. B. adolescentis group, B. bifidum and B. pseudolongum showed a unimodal distribution consisting of only susceptible wild type population (cut-offs ≤ 0.25 μg/ml, ≤ 0.12 μg/ml, and ≤ 0.5 μg/ml, respectively). Eleven potentially erythromycin resistant strains representing B. animalis, B. longum group, B. catenulatum group and B. thermophilum were detected (cut-off for the groups being ≤ 0.25 μg/ml, ≤ 0.25 μg/ml, ≤ 0.25 μg/ml, and ≤ 1 μg/ml, respectively). All studied Bifidobacterium species/groups were intrinsically resistant to streptomycin and susceptible to vancomycin (cut-offs for B. adolescentis group, B. catenulatum group, B. animalis strains being ≤ 1 μg/ml, for B. longum group and B. bifidum ≤ 2 μg/ml, and for B. thermophilum, B.pseudolongum ≤ 1 μg/ml vancomycin).

KW - Bifidobacterium

KW - tetracycline

KW - erythromycin

KW - streptomycin

KW - vancomycin

M3 - Article

VL - 3

SP - 269

EP - 270

JO - International Journal of Probiotics and Prebiotics

JF - International Journal of Probiotics and Prebiotics

SN - 1555-1431

IS - 4

ER -