Systems biology in pharmaceutical R&D

Matej Orešič

Research output: Contribution to journalArticle in a proceedings journalScientific


Emergence of systems biology is expected to have a large impact on pharmaceutical R&D. Systems approaches will be useful in characterization of complex responses to therapeutic interventions in non-clinical studies and discovery research, as well as for providing better predictive models for drug safety and efficacy in clinical phases. Specific examples from clinical studies of lipid lowering drugs, schizophrenia, and type 1 diabetes will be used to illustrate the potential of systems biology in pharmaceutical R&D.
Original languageEnglish
Pages (from-to)S23
JournalEuropean Journal of Pharmaceutical Sciences
Issue number1 supplement 9
Publication statusPublished - 2008
MoE publication typeB3 Non-refereed article in conference proceedings
Event19th Helsinki Drug Research 2008 - Helsinki, Finland
Duration: 9 Jun 200811 Jun 2008


  • systems biology
  • drug discovery
  • drugs
  • drug safety
  • pharmaceutical
  • pharmaceutical industry


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