TEM imaging of mass-selected polymer molecules

Albert Nasibulin, Esko Kauppinen, Bruce Thomson, J. Fernandez de la Mora

Research output: Contribution to journalArticleScientificpeer-review

11 Citations (Scopus)

Abstract

Polyethylene glycol (PEG) molecules with masses below 1300 amu are electrosprayed (ES) from solution, mobility-selected at high resolution in a differential mobility analyzer (DMA), collected on a grid and imaged by transmission electron microscopy (ES–DMA–TEM). The DMA resolves individual n-mers, and selects only one out of the many present in the original sample. Ion identity is established from parallel mass spectra (ES-MS). The images reveal spherical particles 1.46 nm in diameter, in good agreement with the known ion mass and bulk density. The DMA-selection technique opens new paths for the study of very small particles.
Original languageEnglish
Pages (from-to)449-453
JournalJournal of Nanoparticle Research
Volume4
Issue number5
DOIs
Publication statusPublished - 2002
MoE publication typeA1 Journal article-refereed

Fingerprint

Polymers
Imaging
Molecules
Ions
Transmission electron microscopy
Imaging techniques
analyzers
transmission electron microscopy
polymers
Polyethylene glycols
molecules
Transmission Electron Microscopy
mass spectra
glycols
polyethylenes
Resolve
ions
High Resolution
grids
Grid

Keywords

  • electrospray
  • DMA
  • differential mobility analyzer
  • MS
  • TEM
  • transmission electron microscopy
  • polymers
  • nanoparticles
  • polymeric nanoparticles
  • aerosols

Cite this

Nasibulin, A., Kauppinen, E., Thomson, B., & Fernandez de la Mora, J. (2002). TEM imaging of mass-selected polymer molecules. Journal of Nanoparticle Research, 4(5), 449-453. https://doi.org/10.1023/A:1021638818228
Nasibulin, Albert ; Kauppinen, Esko ; Thomson, Bruce ; Fernandez de la Mora, J. / TEM imaging of mass-selected polymer molecules. In: Journal of Nanoparticle Research. 2002 ; Vol. 4, No. 5. pp. 449-453.
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Nasibulin, A, Kauppinen, E, Thomson, B & Fernandez de la Mora, J 2002, 'TEM imaging of mass-selected polymer molecules', Journal of Nanoparticle Research, vol. 4, no. 5, pp. 449-453. https://doi.org/10.1023/A:1021638818228

TEM imaging of mass-selected polymer molecules. / Nasibulin, Albert; Kauppinen, Esko; Thomson, Bruce; Fernandez de la Mora, J.

In: Journal of Nanoparticle Research, Vol. 4, No. 5, 2002, p. 449-453.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - TEM imaging of mass-selected polymer molecules

AU - Nasibulin, Albert

AU - Kauppinen, Esko

AU - Thomson, Bruce

AU - Fernandez de la Mora, J.

PY - 2002

Y1 - 2002

N2 - Polyethylene glycol (PEG) molecules with masses below 1300 amu are electrosprayed (ES) from solution, mobility-selected at high resolution in a differential mobility analyzer (DMA), collected on a grid and imaged by transmission electron microscopy (ES–DMA–TEM). The DMA resolves individual n-mers, and selects only one out of the many present in the original sample. Ion identity is established from parallel mass spectra (ES-MS). The images reveal spherical particles 1.46 nm in diameter, in good agreement with the known ion mass and bulk density. The DMA-selection technique opens new paths for the study of very small particles.

AB - Polyethylene glycol (PEG) molecules with masses below 1300 amu are electrosprayed (ES) from solution, mobility-selected at high resolution in a differential mobility analyzer (DMA), collected on a grid and imaged by transmission electron microscopy (ES–DMA–TEM). The DMA resolves individual n-mers, and selects only one out of the many present in the original sample. Ion identity is established from parallel mass spectra (ES-MS). The images reveal spherical particles 1.46 nm in diameter, in good agreement with the known ion mass and bulk density. The DMA-selection technique opens new paths for the study of very small particles.

KW - electrospray

KW - DMA

KW - differential mobility analyzer

KW - MS

KW - TEM

KW - transmission electron microscopy

KW - polymers

KW - nanoparticles

KW - polymeric nanoparticles

KW - aerosols

U2 - 10.1023/A:1021638818228

DO - 10.1023/A:1021638818228

M3 - Article

VL - 4

SP - 449

EP - 453

JO - Journal of Nanoparticle Research

JF - Journal of Nanoparticle Research

SN - 1388-0764

IS - 5

ER -

Nasibulin A, Kauppinen E, Thomson B, Fernandez de la Mora J. TEM imaging of mass-selected polymer molecules. Journal of Nanoparticle Research. 2002;4(5):449-453. https://doi.org/10.1023/A:1021638818228