TEM imaging of mass-selected polymer molecules

Albert Nasibulin; Esko Kauppinen; Bruce Thomson; J. Fernandez de la Mora

doi:10.1023/A:1021638818228

TEM imaging of mass-selected polymer molecules

Albert Nasibulin, Esko Kauppinen, Bruce Thomson, J. Fernandez de la Mora

VTT Technical Research Centre of Finland

Research output: Contribution to journal › Article › Scientific › peer-review

11 Citations (Scopus)

Abstract

Polyethylene glycol (PEG) molecules with masses below 1300 amu are electrosprayed (ES) from solution, mobility-selected at high resolution in a differential mobility analyzer (DMA), collected on a grid and imaged by transmission electron microscopy (ES–DMA–TEM). The DMA resolves individual n-mers, and selects only one out of the many present in the original sample. Ion identity is established from parallel mass spectra (ES-MS). The images reveal spherical particles 1.46 nm in diameter, in good agreement with the known ion mass and bulk density. The DMA-selection technique opens new paths for the study of very small particles.

Original language	English
Pages (from-to)	449-453
Journal	Journal of Nanoparticle Research
Volume	4
Issue number	5
DOIs	https://doi.org/10.1023/A:1021638818228
Publication status	Published - 2002
MoE publication type	A1 Journal article-refereed

Keywords

electrospray
DMA
differential mobility analyzer
MS
TEM
transmission electron microscopy
polymers
nanoparticles
polymeric nanoparticles
aerosols

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10.1023/A:1021638818228

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title = "TEM imaging of mass-selected polymer molecules",

abstract = "Polyethylene glycol (PEG) molecules with masses below 1300 amu are electrosprayed (ES) from solution, mobility-selected at high resolution in a differential mobility analyzer (DMA), collected on a grid and imaged by transmission electron microscopy (ES–DMA–TEM). The DMA resolves individual n-mers, and selects only one out of the many present in the original sample. Ion identity is established from parallel mass spectra (ES-MS). The images reveal spherical particles 1.46 nm in diameter, in good agreement with the known ion mass and bulk density. The DMA-selection technique opens new paths for the study of very small particles.",

keywords = "electrospray, DMA, differential mobility analyzer, MS, TEM, transmission electron microscopy, polymers, nanoparticles, polymeric nanoparticles, aerosols",

author = "Albert Nasibulin and Esko Kauppinen and Bruce Thomson and {Fernandez de la Mora}, J.",

year = "2002",

doi = "10.1023/A:1021638818228",

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pages = "449--453",

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T1 - TEM imaging of mass-selected polymer molecules

AU - Nasibulin, Albert

AU - Kauppinen, Esko

AU - Thomson, Bruce

AU - Fernandez de la Mora, J.

PY - 2002

Y1 - 2002

N2 - Polyethylene glycol (PEG) molecules with masses below 1300 amu are electrosprayed (ES) from solution, mobility-selected at high resolution in a differential mobility analyzer (DMA), collected on a grid and imaged by transmission electron microscopy (ES–DMA–TEM). The DMA resolves individual n-mers, and selects only one out of the many present in the original sample. Ion identity is established from parallel mass spectra (ES-MS). The images reveal spherical particles 1.46 nm in diameter, in good agreement with the known ion mass and bulk density. The DMA-selection technique opens new paths for the study of very small particles.

AB - Polyethylene glycol (PEG) molecules with masses below 1300 amu are electrosprayed (ES) from solution, mobility-selected at high resolution in a differential mobility analyzer (DMA), collected on a grid and imaged by transmission electron microscopy (ES–DMA–TEM). The DMA resolves individual n-mers, and selects only one out of the many present in the original sample. Ion identity is established from parallel mass spectra (ES-MS). The images reveal spherical particles 1.46 nm in diameter, in good agreement with the known ion mass and bulk density. The DMA-selection technique opens new paths for the study of very small particles.

KW - electrospray

KW - DMA

KW - differential mobility analyzer

KW - MS

KW - TEM

KW - transmission electron microscopy

KW - polymers

KW - nanoparticles

KW - polymeric nanoparticles

KW - aerosols

U2 - 10.1023/A:1021638818228

DO - 10.1023/A:1021638818228

M3 - Article

SN - 1388-0764

VL - 4

SP - 449

EP - 453

JO - Journal of Nanoparticle Research

JF - Journal of Nanoparticle Research

IS - 5

ER -

TEM imaging of mass-selected polymer molecules

Abstract

Keywords

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