The 2008 update of the Aspergillus nidulans genome annotation

A community effort

J.R. Wortman, J.M. Gilsenan, V. Joardar, J. Deegan, J. Clutterbuck, M.R. Andersen, D. Archer, M. Bencina, G. Braus, P. Coutinho, H. von Döhren, J. Doonan, A.J.M. Driessen, P. Durek, E. Espeso, E. Fekete, Tiina Pakula, Geoffrey Turner (Corresponding Author), et al

Research output: Contribution to journalArticleScientificpeer-review

68 Citations (Scopus)

Abstract

The identification and annotation of protein-coding genes is one of the primary goals of whole-genome sequencing projects, and the accuracy of predicting the primary protein products of gene expression is vital to the interpretation of the available data and the design of downstream functional applications. Nevertheless, the comprehensive annotation of eukaryotic genomes remains a considerable challenge. Many genomes submitted to public databases, including those of major model organisms, contain significant numbers of wrong and incomplete gene predictions. We present a community-based reannotation of the Aspergillus nidulans genome with the primary goal of increasing the number and quality of protein functional assignments through the careful review of experts in the field of fungal biology.
Original languageEnglish
Pages (from-to)S2-S13
Number of pages12
JournalFungal Genetics and Biology
Volume46
Issue number1
DOIs
Publication statusPublished - 2009
MoE publication typeA1 Journal article-refereed

Fingerprint

Aspergillus nidulans
Genome
Molecular Sequence Annotation
Proteins
Databases
Gene Expression
Genes

Keywords

  • Aspergillus nidulans
  • Aspergilli
  • Genome
  • Annotation
  • Fungal community
  • Assembly
  • Transcription factors
  • CADRE

Cite this

Wortman, J. R., Gilsenan, J. M., Joardar, V., Deegan, J., Clutterbuck, J., Andersen, M. R., ... al, E. (2009). The 2008 update of the Aspergillus nidulans genome annotation: A community effort. Fungal Genetics and Biology, 46(1), S2-S13. https://doi.org/10.1016/j.fgb.2008.12.003
Wortman, J.R. ; Gilsenan, J.M. ; Joardar, V. ; Deegan, J. ; Clutterbuck, J. ; Andersen, M.R. ; Archer, D. ; Bencina, M. ; Braus, G. ; Coutinho, P. ; von Döhren, H. ; Doonan, J. ; Driessen, A.J.M. ; Durek, P. ; Espeso, E. ; Fekete, E. ; Pakula, Tiina ; Turner, Geoffrey ; al, et. / The 2008 update of the Aspergillus nidulans genome annotation : A community effort. In: Fungal Genetics and Biology. 2009 ; Vol. 46, No. 1. pp. S2-S13.
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Wortman, JR, Gilsenan, JM, Joardar, V, Deegan, J, Clutterbuck, J, Andersen, MR, Archer, D, Bencina, M, Braus, G, Coutinho, P, von Döhren, H, Doonan, J, Driessen, AJM, Durek, P, Espeso, E, Fekete, E, Pakula, T, Turner, G & al, E 2009, 'The 2008 update of the Aspergillus nidulans genome annotation: A community effort', Fungal Genetics and Biology, vol. 46, no. 1, pp. S2-S13. https://doi.org/10.1016/j.fgb.2008.12.003

The 2008 update of the Aspergillus nidulans genome annotation : A community effort. / Wortman, J.R.; Gilsenan, J.M.; Joardar, V.; Deegan, J.; Clutterbuck, J.; Andersen, M.R.; Archer, D.; Bencina, M.; Braus, G.; Coutinho, P.; von Döhren, H.; Doonan, J.; Driessen, A.J.M.; Durek, P.; Espeso, E.; Fekete, E.; Pakula, Tiina; Turner, Geoffrey (Corresponding Author); al, et.

In: Fungal Genetics and Biology, Vol. 46, No. 1, 2009, p. S2-S13.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - The 2008 update of the Aspergillus nidulans genome annotation

T2 - A community effort

AU - Wortman, J.R.

AU - Gilsenan, J.M.

AU - Joardar, V.

AU - Deegan, J.

AU - Clutterbuck, J.

AU - Andersen, M.R.

AU - Archer, D.

AU - Bencina, M.

AU - Braus, G.

AU - Coutinho, P.

AU - von Döhren, H.

AU - Doonan, J.

AU - Driessen, A.J.M.

AU - Durek, P.

AU - Espeso, E.

AU - Fekete, E.

AU - Pakula, Tiina

AU - Turner, Geoffrey

AU - al, et

PY - 2009

Y1 - 2009

N2 - The identification and annotation of protein-coding genes is one of the primary goals of whole-genome sequencing projects, and the accuracy of predicting the primary protein products of gene expression is vital to the interpretation of the available data and the design of downstream functional applications. Nevertheless, the comprehensive annotation of eukaryotic genomes remains a considerable challenge. Many genomes submitted to public databases, including those of major model organisms, contain significant numbers of wrong and incomplete gene predictions. We present a community-based reannotation of the Aspergillus nidulans genome with the primary goal of increasing the number and quality of protein functional assignments through the careful review of experts in the field of fungal biology.

AB - The identification and annotation of protein-coding genes is one of the primary goals of whole-genome sequencing projects, and the accuracy of predicting the primary protein products of gene expression is vital to the interpretation of the available data and the design of downstream functional applications. Nevertheless, the comprehensive annotation of eukaryotic genomes remains a considerable challenge. Many genomes submitted to public databases, including those of major model organisms, contain significant numbers of wrong and incomplete gene predictions. We present a community-based reannotation of the Aspergillus nidulans genome with the primary goal of increasing the number and quality of protein functional assignments through the careful review of experts in the field of fungal biology.

KW - Aspergillus nidulans

KW - Aspergilli

KW - Genome

KW - Annotation

KW - Fungal community

KW - Assembly

KW - Transcription factors

KW - CADRE

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DO - 10.1016/j.fgb.2008.12.003

M3 - Article

VL - 46

SP - S2-S13

JO - Fungal Genetics and Biology

JF - Fungal Genetics and Biology

SN - 1087-1845

IS - 1

ER -

Wortman JR, Gilsenan JM, Joardar V, Deegan J, Clutterbuck J, Andersen MR et al. The 2008 update of the Aspergillus nidulans genome annotation: A community effort. Fungal Genetics and Biology. 2009;46(1):S2-S13. https://doi.org/10.1016/j.fgb.2008.12.003