The 2008 update of the Aspergillus nidulans genome annotation: A community effort

J.R. Wortman, J.M. Gilsenan, V. Joardar, J. Deegan, J. Clutterbuck, M.R. Andersen, D. Archer, M. Bencina, G. Braus, P. Coutinho, H. von Döhren, J. Doonan, A.J.M. Driessen, P. Durek, E. Espeso, E. Fekete, Tiina Pakula, Geoffrey Turner (Corresponding Author), et al

    Research output: Contribution to journalArticleScientificpeer-review

    74 Citations (Scopus)

    Abstract

    The identification and annotation of protein-coding genes is one of the primary goals of whole-genome sequencing projects, and the accuracy of predicting the primary protein products of gene expression is vital to the interpretation of the available data and the design of downstream functional applications. Nevertheless, the comprehensive annotation of eukaryotic genomes remains a considerable challenge. Many genomes submitted to public databases, including those of major model organisms, contain significant numbers of wrong and incomplete gene predictions. We present a community-based reannotation of the Aspergillus nidulans genome with the primary goal of increasing the number and quality of protein functional assignments through the careful review of experts in the field of fungal biology.
    Original languageEnglish
    Pages (from-to)S2-S13
    Number of pages12
    JournalFungal Genetics and Biology
    Volume46
    Issue number1
    DOIs
    Publication statusPublished - 2009
    MoE publication typeA1 Journal article-refereed

    Keywords

    • Aspergillus nidulans
    • Aspergilli
    • Genome
    • Annotation
    • Fungal community
    • Assembly
    • Transcription factors
    • CADRE

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