The effect of a staphylococcal cell wall factor on the early inflammatory response to staphylococcal infection of the lactating bovine udder

Tiina Mattila, Denise O'Boyle, Alan Frost

Research output: Contribution to journalArticleScientificpeer-review

1 Citation (Scopus)

Abstract

The effect on the early inflammatory response in the bovine mammary gland of a factor extracted from the cell wall of Staphylococcus aureus was studied.
The insoluble factor was extracted from a 3h‐culture, and was mixed with S. aureus from an overnight culture (OF) for experimental infection of a lactating quarter. Other quarters were infected with a 3h or an overnight culture (O). Five cows were used in the experiment.
The O‐quarters showed more severe clinical signs than seen in the 3h‐and OF quarters. Antitrypsin levels and NAGase concentrations were much reduced in the 3h‐and OF‐quarters.
While the cell wall factor profoundly reduced the early inflammatory response, the effect on the final outcome of the infection was not determined.
Original languageEnglish
Pages (from-to)114-117
JournalAustralian Veterinary Journal
Volume65
Issue number4
DOIs
Publication statusPublished - 1988
MoE publication typeA1 Journal article-refereed

Fingerprint

Staphylococcal Infections
Animal Mammary Glands
udders
Cell Wall
Staphylococcus aureus
inflammation
cell walls
STAT5 Transcription Factor
beta-N-acetylhexosaminidase
Acetylglucosaminidase
cattle
Infection
mammary glands
infection
cows

Cite this

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title = "The effect of a staphylococcal cell wall factor on the early inflammatory response to staphylococcal infection of the lactating bovine udder",
abstract = "The effect on the early inflammatory response in the bovine mammary gland of a factor extracted from the cell wall of Staphylococcus aureus was studied. The insoluble factor was extracted from a 3h‐culture, and was mixed with S. aureus from an overnight culture (OF) for experimental infection of a lactating quarter. Other quarters were infected with a 3h or an overnight culture (O). Five cows were used in the experiment. The O‐quarters showed more severe clinical signs than seen in the 3h‐and OF quarters. Antitrypsin levels and NAGase concentrations were much reduced in the 3h‐and OF‐quarters. While the cell wall factor profoundly reduced the early inflammatory response, the effect on the final outcome of the infection was not determined.",
author = "Tiina Mattila and Denise O'Boyle and Alan Frost",
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The effect of a staphylococcal cell wall factor on the early inflammatory response to staphylococcal infection of the lactating bovine udder. / Mattila, Tiina; O'Boyle, Denise; Frost, Alan.

In: Australian Veterinary Journal, Vol. 65, No. 4, 1988, p. 114-117.

Research output: Contribution to journalArticleScientificpeer-review

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T1 - The effect of a staphylococcal cell wall factor on the early inflammatory response to staphylococcal infection of the lactating bovine udder

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AU - Frost, Alan

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AB - The effect on the early inflammatory response in the bovine mammary gland of a factor extracted from the cell wall of Staphylococcus aureus was studied. The insoluble factor was extracted from a 3h‐culture, and was mixed with S. aureus from an overnight culture (OF) for experimental infection of a lactating quarter. Other quarters were infected with a 3h or an overnight culture (O). Five cows were used in the experiment. The O‐quarters showed more severe clinical signs than seen in the 3h‐and OF quarters. Antitrypsin levels and NAGase concentrations were much reduced in the 3h‐and OF‐quarters. While the cell wall factor profoundly reduced the early inflammatory response, the effect on the final outcome of the infection was not determined.

U2 - 10.1111/j.1751-0813.1988.tb14428.x

DO - 10.1111/j.1751-0813.1988.tb14428.x

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