@inproceedings{0dc3a8ad503a41f2a7d4dd536e096237,
title = "The effect of laser irradiation on living cells incubated with gold nanoparticles",
abstract = "Plasmon-resonant nanoparticles attached to cell membranes, under laser treatment can temporarily increase membrane permeability. In this paper, the influence of continuous-wave and pulsed (nanosecond) laser irradiation on living cells incubated with gold nanoparticles was investigated. Gold nanospheres, nanostars, and nanorods with different functionalization were used as plasmonic agents. The dependence between increase of medium temperature on the irradiation time was showed for nanostars and nanorods with different surface properties. Cells samples incubated with gold nanorods showed the highest temperature increase. Feasibility of cell optoporation by the use of gold nanospheres with variable functionalization was demonstrated. The cell membrane permeability was successfully enhanced as shown by the uptake of the fluorescent dye upon nanosecond laser treatment. Toxicity of the nanoparticles was estimated by MTT assay.",
keywords = "Continuous wave laser, Irradiation, Nanorods, Nanosecond laser, Nanospheres, Nanostars, Optoporation, Plasmon-resonant gold nanoparticles",
author = "Olga Bibikova and Prateek Singh and Alexey Popov and Georgy Akchurin and Ilya Skovorodkin and Vitaly Khanadeev and Matti Kinnunen and Vladimir Bogatyrev and Nikolai Khlebtsov and Seppo Vainio and Valery Tuchin",
year = "2015",
month = jan,
day = "1",
doi = "10.1117/12.2083023",
language = "English",
isbn = "978-1-6284-1430-1",
series = "Progress in Biomedical Optics and Imaging",
publisher = "International Society for Optics and Photonics SPIE",
number = "38",
editor = "Lakowicz, {Joseph R.} and Tuan Vo-Dinh",
booktitle = "Plasmonics in Biology and Medicine XII",
address = "United States",
note = "Plasmonics in Biology and Medicine XII ; Conference date: 07-02-2015 Through 08-02-2015",
}