The relation between solution association and surface activity of the hydrophobin HFBI from Trichoderma reesei

Geza Szilvay (Corresponding Author), Kaisa Kisko, Ritva Serimaa, Markus Linder

    Research output: Contribution to journalArticleScientificpeer-review

    26 Citations (Scopus)

    Abstract

    Hydrophobins are small fungal surface active proteins that self-assemble at interfaces into films with nanoscale structures. The hydrophobin HFBI from Trichoderma reesei has been shown to associate in solution into tetramers but the role of this association on the function of HFBI has remained unclear. We produced two HFBI variants that showed a significant shift in solution association equilibrium towards the tetramer state. However, this enhanced solution association did not alter the surface properties of the variant HFBIs. The results show that there is not a strong relationship between HFBI solution association state and surface properties such as surface activity.
    Original languageEnglish
    Pages (from-to)2721-2726
    JournalFEBS Letters
    Volume581
    Issue number14
    DOIs
    Publication statusPublished - 2007
    MoE publication typeA1 Journal article-refereed

    Keywords

    • hydrophobins
    • Protein multimerization
    • Protein self-assembly
    • Surface active protein

    Fingerprint

    Dive into the research topics of 'The relation between solution association and surface activity of the hydrophobin HFBI from Trichoderma reesei'. Together they form a unique fingerprint.

    Cite this