Tissue-mimicking phantoms for biomedical applications

Oleksii Sieryi, Alexey Popov, Vyacheslav Kalchenko, Alexander Bykov, Igor Meglinski

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

Abstract

Emerging biomedical instrumentation for imaging and diagnostics requires tissue-mimicking phantoms with optical properties close to those of real biological tissues. Many such tissues and organs consist of several layers with different physical properties, e.g. the head includes the brain, skull, and skin, which in turn also comprise several layers. Structure, optical and mechanical properties depend on the purpose of phantoms and studied materials and technologies. In this paper, we present both plain single-, multi-layered phantoms, and complex opto-mechanical phantoms that imitate parts of the body, in particular, the head. We describe the procedure, materials, internal structure, and tuning of the optical properties of two different phantom manufacturing methods as well as show examples of tissue-mimicking phantoms for different biomedical applications.

Original languageEnglish
Title of host publicationTissue Optics and Photonics
EditorsValery V. Tuchin, Walter C. P. M. Blondel, Zeev Zalevsky
PublisherInternational Society for Optics and Photonics SPIE
ISBN (Electronic)9781510634985
DOIs
Publication statusPublished - 20 May 2020
MoE publication typeA4 Article in a conference publication
EventSPIE Photonics Europe Digital Forum 2020
: Online Only
- None, France
Duration: 6 Apr 202010 Apr 2020

Publication series

SeriesProceedings of SPIE - The International Society for Optical Engineering
Volume11363
ISSN0277-786X

Conference

ConferenceSPIE Photonics Europe Digital Forum 2020
CountryFrance
CityNone
Period6/04/2010/04/20

Keywords

  • Biomedical
  • Head phantom
  • Optical properties
  • Phantoms
  • Tissue-mimicking

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  • Cite this

    Sieryi, O., Popov, A., Kalchenko, V., Bykov, A., & Meglinski, I. (2020). Tissue-mimicking phantoms for biomedical applications. In V. V. Tuchin, W. C. P. M. Blondel, & Z. Zalevsky (Eds.), Tissue Optics and Photonics [1136312] International Society for Optics and Photonics SPIE. Proceedings of SPIE - The International Society for Optical Engineering, Vol.. 11363 https://doi.org/10.1117/12.2560174