Tissue-mimicking phantoms for biomedical applications

Oleksii Sieryi; Alexey Popov; Vyacheslav Kalchenko; Alexander Bykov; Igor Meglinski

doi:10.1117/12.2560174

Tissue-mimicking phantoms for biomedical applications

Oleksii Sieryi
, Alexey Popov
, Vyacheslav Kalchenko
, Alexander Bykov
, Igor Meglinski

University of Oulu
Weizmann Institute of Science
Aston University
National Research Tomsk State University
National Research Nuclear University (MEPhI)

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

18 Citations (Scopus)

Abstract

Emerging biomedical instrumentation for imaging and diagnostics requires tissue-mimicking phantoms with optical properties close to those of real biological tissues. Many such tissues and organs consist of several layers with different physical properties, e.g. the head includes the brain, skull, and skin, which in turn also comprise several layers. Structure, optical and mechanical properties depend on the purpose of phantoms and studied materials and technologies. In this paper, we present both plain single-, multi-layered phantoms, and complex opto-mechanical phantoms that imitate parts of the body, in particular, the head. We describe the procedure, materials, internal structure, and tuning of the optical properties of two different phantom manufacturing methods as well as show examples of tissue-mimicking phantoms for different biomedical applications.

Original language	English
Title of host publication	Tissue Optics and Photonics
Editors	Valery V. Tuchin, Walter C. P. M. Blondel, Zeev Zalevsky
Place of Publication	Bellingham
Publisher	International Society for Optics and Photonics SPIE
ISBN (Print)	978-1-5106-3498-5
DOIs	https://doi.org/10.1117/12.2560174
Publication status	Published - 20 May 2020
MoE publication type	A4 Article in a conference publication
Event	SPIE Photonics Europe Digital Forum 2020 : Online Only - None, France Duration: 6 Apr 2020 → 10 Apr 2020

Publication series

Series	Proceedings of SPIE
Volume	11363
ISSN	0277-786X

Conference

Conference	SPIE Photonics Europe Digital Forum 2020
Country/Territory	France
City	None
Period	6/04/20 → 10/04/20

Funding

This project has received funding from the ATTRACT project funded by the EC under Grant Agreement 777222 and partially by Academy of Finland (grant: 325097, 314369). IM also acknowledges partial support from MEPhI Academic Excellence Project (Contract No. 02.a03.21.0005), Russian Science Foundation (Project 19-72-30012) and the National Research Tomsk State University Academic D.I. Mendeleev Fund Program.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 9 Industry, Innovation, and Infrastructure

Keywords

Biomedical
Head phantom
Optical properties
Phantoms
Tissue-mimicking

Access to Document

10.1117/12.2560174

Cite this

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title = "Tissue-mimicking phantoms for biomedical applications",

abstract = "Emerging biomedical instrumentation for imaging and diagnostics requires tissue-mimicking phantoms with optical properties close to those of real biological tissues. Many such tissues and organs consist of several layers with different physical properties, e.g. the head includes the brain, skull, and skin, which in turn also comprise several layers. Structure, optical and mechanical properties depend on the purpose of phantoms and studied materials and technologies. In this paper, we present both plain single-, multi-layered phantoms, and complex opto-mechanical phantoms that imitate parts of the body, in particular, the head. We describe the procedure, materials, internal structure, and tuning of the optical properties of two different phantom manufacturing methods as well as show examples of tissue-mimicking phantoms for different biomedical applications.",

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author = "Oleksii Sieryi and Alexey Popov and Vyacheslav Kalchenko and Alexander Bykov and Igor Meglinski",

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booktitle = "Tissue Optics and Photonics",

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note = "SPIE Photonics Europe Digital Forum 2020<br/> : Online Only ; Conference date: 06-04-2020 Through 10-04-2020",

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Sieryi, O, Popov, A, Kalchenko, V, Bykov, A & Meglinski, I 2020, Tissue-mimicking phantoms for biomedical applications. in VV Tuchin, WCPM Blondel & Z Zalevsky (eds), Tissue Optics and Photonics., 1136312, International Society for Optics and Photonics SPIE, Bellingham, Proceedings of SPIE, vol. 11363, SPIE Photonics Europe Digital Forum 2020
, None, France, 6/04/20. https://doi.org/10.1117/12.2560174

Tissue-mimicking phantoms for biomedical applications. / Sieryi, Oleksii; Popov, Alexey; Kalchenko, Vyacheslav et al.
Tissue Optics and Photonics. ed. / Valery V. Tuchin; Walter C. P. M. Blondel; Zeev Zalevsky. Bellingham: International Society for Optics and Photonics SPIE, 2020. 1136312 (Proceedings of SPIE, Vol. 11363).

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

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AU - Popov, Alexey

AU - Kalchenko, Vyacheslav

AU - Bykov, Alexander

AU - Meglinski, Igor

PY - 2020/5/20

Y1 - 2020/5/20

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AB - Emerging biomedical instrumentation for imaging and diagnostics requires tissue-mimicking phantoms with optical properties close to those of real biological tissues. Many such tissues and organs consist of several layers with different physical properties, e.g. the head includes the brain, skull, and skin, which in turn also comprise several layers. Structure, optical and mechanical properties depend on the purpose of phantoms and studied materials and technologies. In this paper, we present both plain single-, multi-layered phantoms, and complex opto-mechanical phantoms that imitate parts of the body, in particular, the head. We describe the procedure, materials, internal structure, and tuning of the optical properties of two different phantom manufacturing methods as well as show examples of tissue-mimicking phantoms for different biomedical applications.

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BT - Tissue Optics and Photonics

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ER -

Tissue-mimicking phantoms for biomedical applications

Abstract

Publication series

Conference

Funding

UN SDGs

Keywords

Access to Document

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