Abstract
Two new haptens were employed as antigens to elicit antibodies for acyl-transfer reactions. The haptens, both α-keto amides were designed to elicit antibodies which could twist potential substrates into a much more reactive conformation. The rationale for their design, synthesis, and immunization protocols will be discussed.
Two α-keto amides 1 and 2 were employed as antigens to elicit antibodies for acyl-transfer reactions. The rationale for their design, synthesis, and immunization protocols will be discussed.
Two α-keto amides 1 and 2 were employed as antigens to elicit antibodies for acyl-transfer reactions. The rationale for their design, synthesis, and immunization protocols will be discussed.
Original language | English |
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Pages (from-to) | 521-528 |
Number of pages | 8 |
Journal | Bioorganic & Medicinal Chemistry |
Volume | 2 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1994 |
MoE publication type | A1 Journal article-refereed |