Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 981-983 |
| Journal | Nature Cell Biology |
| Volume | 14 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2012 |
| MoE publication type | A1 Journal article-refereed |
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Unanchoring integrins in focal adhesions. / Ivaska, Johanna (Corresponding Author).
In: Nature Cell Biology, Vol. 14, No. 10, 2012, p. 981-983.Research output: Contribution to journal › Article › Scientific › peer-review
TY - JOUR
T1 - Unanchoring integrins in focal adhesions
AU - Ivaska, Johanna
PY - 2012
Y1 - 2012
N2 - Focal adhesions are large structures through which integrins and scaffold proteins link the actin cytoskeleton to the extracellular matrix. A detailed analysis of integrin dynamics now indicates that focal-adhesion-associated integrins constantly switch between active and immobilized, and unbound and free-diffusing states, with different fibronectin-binding integrin heterodimers showing distinct focal-adhesion dynamics.
AB - Focal adhesions are large structures through which integrins and scaffold proteins link the actin cytoskeleton to the extracellular matrix. A detailed analysis of integrin dynamics now indicates that focal-adhesion-associated integrins constantly switch between active and immobilized, and unbound and free-diffusing states, with different fibronectin-binding integrin heterodimers showing distinct focal-adhesion dynamics.
U2 - 10.1038/ncb2592
DO - 10.1038/ncb2592
M3 - Article
VL - 14
SP - 981
EP - 983
JO - Nature Cell Biology
JF - Nature Cell Biology
SN - 1465-7392
IS - 10
ER -