Utilization of a multimembrane inlet and a cyclic sudden sampling introduction mode in membrane inlet mass spectrometry

O. S. Viktorova, V. T. Kogan (Corresponding Author), S. A. Manninen, T. Kotiaho, Raimo Ketola, B.M. Dubenskii, S.P. Parinov, O.V. Smirnov

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Abstract

Sudden sampling introduction into a membrane inlet mass spectrometer (MIMS) considerably improves the selectivity of the membrane inlet and is therefore applicable even for compounds with low permeabilities through a silicone membrane. In this study the basics of cyclic non-steady-state sudden increase sample injection were studied using a three-membrane inlet and a portable sector double-focusing mass spectrometer. The operational parameters of the inlet system providing the most efficient enrichment of volatile organic compounds (VOCs) in air were defined. Simulation of the diffusion process following sudden sample introduction into the three-membrane inlet was also carried out. Experimental testing of the three-membrane inlet system with the cyclic sudden sample injection mode for benzene, toluene, styrene, and xylene in air was performed. The simulation and the experimental results demonstrated that, when this mode is used, the VOCs/nitrogen relative enrichment factor of samples introduced into the mass spectrometer equipped with a three-membrane inlet is increased by a factor of ∼105 compared with a direct introduction method. This effect may be used to decrease detection limits of compounds obtained with mass spectrometry to decrease matrix flow through the inlet at the same detection limits.
Original languageEnglish
Pages (from-to)823-831
JournalJournal of the American Society for Mass Spectrometry
Volume15
Issue number6
DOIs
Publication statusPublished - 2004
MoE publication typeA1 Journal article-refereed

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Keywords

  • membrane inlet mass spectrometry
  • MIMS
  • volatile organic compounds
  • VOC

Cite this

Viktorova, O. S., Kogan, V. T., Manninen, S. A., Kotiaho, T., Ketola, R., Dubenskii, B. M., Parinov, S. P., & Smirnov, O. V. (2004). Utilization of a multimembrane inlet and a cyclic sudden sampling introduction mode in membrane inlet mass spectrometry. Journal of the American Society for Mass Spectrometry, 15(6), 823-831. https://doi.org/10.1016/j.jasms.2004.02.002