VTT systems biology and bioinformatics: A framework for the integration of biotechnology, information technology and engineering

Matej Oresic (Corresponding author), Merja Penttilä, Jyrki Lötjönen, Kaisa Poutanen, Hans Söderlund

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsScientific


    VTT Technical Research Centre of Finland is an impartial expert organisation. Systems biology at VTT aims to integrate a broad range of in-house expertise. The systems biology platform combines bioinformatics with molecular profiling approaches and new measurement technologies, and benefits from inhouse
    knowledge across information technology, biosensors, microbiology, plants, nutrition, and medical domains. We will highlight four projects from different biotechnology and medical domains where the VTT’s systems biology plays an
    important role:
    (1) The Finnish Centre of Excellence in White Biotechnology - Green Chemistry Research is a Centre of Excellence suppoirted by the Academy of Finland. Its main aim is to develop efficient microbes and processes for the production of chemicals from plant biomass sugars.
    (2) PredictAD (From patient data to personalized healthcare in Alzheimer’s disease) is an EU FP7-ICT (Virtual Physiological Human) funded research project aiming at developing a standardised and objective solution that would enable an
    earlier diagnosis of Alzheimer’s disease, improved monitoring of treatment efficacy and enhanced cost-effectiveness of diagnostic protocols.
    (3) AtheroRemo (European Collaborative Project on Inflammation and Vascular Wall Remodelling in Atherosclerosis) is an EU FP7-Health funded research project aiming to identify novel inflammatory mechanisms in vascular remodelling by combining the exploration of human biobanks with animal models and
    established cellular models. This new knowledge will be used to develop new preventive, diagnostic and therapeutic strategies against atherosclerotic cardiovascular disease.
    (4) SYSDIET (Systems biology in controlled dietary interventions and cohort studies) is a Nordic Centre of Excellence funded by Nordforsk. SYSDIET aims at a coordinated effort for exploitation of nutrigenomics/systems biology tools in human randomized controlled dietary interventions and animal and cell culture studies in order to find out novel mechanisms by which Nordic foods and diets could be modified to promote health and prevent chronic diseases.
    Original languageEnglish
    Title of host publicationThe 9th International Conference on Systems Biology (ICSB 2008)
    Subtitle of host publicationAbstract Book
    Publication statusPublished - 2008
    Event9th International Conference on Systems Biology, ICSB2008 - Göteborg, Sweden
    Duration: 22 Aug 200828 Aug 2008


    Conference9th International Conference on Systems Biology, ICSB2008
    Abbreviated titleICSB2008


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