Merja Penttilä

  • Phone+358407000163
1980 …2020

Research output per year

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Personal profile

Research interests

My main responsibility is to advance science and technology in the fields of Industrial Biotechnology and Synthetic biology. At VTT this research consists of ~90 people, with expertise in metabolic engineering, protein production, plant biotechnology, metabolomics, enzymology, synthetic biology, and bioprocessing. I have supervised or co-supervised ~25 doctoral theses.

Education/Academic qualification

Doctorate, University of Helsinki

Award Date: 1 Sep 1987

External positions

Adjunct professor, Aalto University

1 Jan 2016 → …

Co-PI of a Finnish Centre of Excellence in Molecular Engineering of Biosynthetic Hybrid Materials Research (HYBER), Academy of Finland


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Research Output

Controllable coacervation of recombinantly produced spider silk protein using kosmotropic salts

Mohammadi, P., Jonkergouw, C., Beaune, G., Engelhardt, P., Kamada, A., Timonen, J. V. I., Knowles, T. P. J., Penttilä, M. & Linder, M. B., 15 Feb 2020, In : Journal of Colloid and Interface Science. 560, p. 149-160 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
  • The Lipomyces starkeyi gene Ls120451 encodes a cellobiose transporter that enables cellobiose fermentation in Saccharomyces cerevisiae

    de Ruijter, J., Igarashi, K. & Penttilä, M., 1 May 2020, In : FEMS Yeast Research. 20, 3, 19 p.

    Research output: Contribution to journalArticleScientificpeer-review

    Open Access
  • Evaluation of synthetic formaldehyde and methanol assimilation pathways in Yarrowia lipolytica

    Vartiainen, E., Blomberg, P., Ilmén, M., Andberg, M., Toivari, M. & Penttilä, M., 17 Dec 2019, In : Fungal Biology and Biotechnology. 6, 27.

    Research output: Contribution to journalArticleScientificpeer-review

    Open Access
  • A High-Throughput Workflow for CRISPR/Cas9 Mediated Combinatorial Promoter Replacements and Phenotype Characterization in Yeast

    Kuivanen, J., Holmström, S., Lehtinen, B., Penttilä, M. & Jäntti, J., 1 Sep 2018, In : Biotechnology Journal. 13, 9, 1700593.

    Research output: Contribution to journalArticleScientificpeer-review

  • 3 Citations (Scopus)

    A universal gene expression system for fungi

    Rantasalo, A., Landowski, C. P., Kuivanen, J., Korppoo, A., Reuter, L., Koivistoinen, O., Valkonen, M., Penttilä, M., Jäntti, J. & Mojzita, D., 1 Jan 2018, In : Nucleic Acids Research. 46, 18, 15 p., e111.

    Research output: Contribution to journalArticleScientificpeer-review

    Open Access
  • 9 Citations (Scopus)


    A design–build–test cycle using modeling and experiments reveals interdependencies between upper glycolysis and xylose uptake in recombinant S. cerevisiae and improves predictive capabilities of large-scale kinetic models

    Miskovic, L. (Contributor), Alff-Tuomala, S. (Contributor), Soh, K. C. (Contributor), Barth, D. (Contributor), Salusjärvi, L. (Contributor), Pitkänen, J. (Contributor), Ruohonen, L. (Contributor), Penttilä, M. (Contributor) & Hatzimanikatis, V. (Contributor), Figshare, 26 Jun 2017